Medication compliance and blood pressure among Prolanis patients with hypertension

Nadzirotul Khazanah (Universitas Islam Sultan Agung Semarang)
Iskim Luthfa (Sultan Agung Islamic University) ROR
Abrori Abrori (Sultan Agung Islamic University) ROR
DOI: 10.56922/msc.v6i6.8 Published: 2026-10-27 pp. 182-186
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Background: Hypertension is a major cause of premature morbidity and mortality. Long-term medication adherence is an important component of blood-pressure management, although blood pressure is also influenced by clinical and behavioural factors beyond medication taking.

Purpose: To examine the association between medication compliance and systolic and diastolic blood pressure among Prolanis patients with hypertension.

Method: This cross-sectional study included 113 Prolanis patients with hypertension at Puskesmas Pandanaran, Semarang. Medication compliance was assessed using the 8-item Morisky Medication Adherence Scale (MMAS-8), and blood pressure was measured using a sphygmomanometer. Unadjusted associations were analysed using Spearman's rank correlation in SPSS version 27.

Results: High medication compliance was reported by 85 respondents (75.2%), moderate compliance by 11 (9.7%), and low compliance by 17 (15.0%). Median systolic blood pressure was 137 mmHg (range 94–177) and median diastolic pressure was 80 mmHg (59–105). Medication compliance was weakly and negatively associated with systolic blood pressure (ρ = −0.248; p = 0.008) and diastolic blood pressure (ρ = −0.196; p = 0.038).

Conclusion: Higher medication compliance was associated with lower systolic and diastolic blood pressure, although both correlations were weak. The cross-sectional design does not establish causality, and blood-pressure control is likely influenced by multiple additional factors.

Medication compliance and blood pressure among Prolanis patients with hypertension. (2026). Journal of Medical Surgical Concerns, 6(6), 182-186. https://doi.org/10.56922/msc.v6i6.8
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